Rabu, 27 Maret 2019

The Design and Analysis of Sequential Clinical Trials 2RevEd 9780471975502 Medicine Health Science Books Free PDF Reader IOM

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  • This book details all aspects of sequential clinical trials from preliminary planning, through the monitoring of the trial, to the final analysis of the results. Emphasis is placed on the triangular test and other procedures based on straight line stopping boundaries. These methods allow for frequent or occasional interim analyses and permit the analysis of a wide variety of patient responses. Alternative procedures are also covered in detail, and these include -spending function methods, repeated confidence intervals and Bayesian approaches to sequential clinical trials.
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    The Design and Analysis of Sequential Clinical Trials 2RevEd 9780471975502 Medicine Health Science Books Reviews :



    This book details all aspects of sequential clinical trials from preliminary planning, through the monitoring of the trial, to the final analysis of the results. Emphasis is placed on the triangular test and other procedures based on straight line stopping boundaries. These methods allow for frequent or occasional interim analyses and permit the analysis of a wide variety of patient responses. Alternative procedures are also covered in detail, and these include -spending function methods, repeated confidence intervals and Bayesian approaches to sequential clinical trials.

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    Product details

    • Hardcover 328 pages
    • Publisher Wiley; 2 edition (July 1997)
    • Language English
    • ISBN-10 0471975508
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    Product details

    • Paperback 1184 pages
    • Publisher Cengage Learning; 7 edition (January 19, 2017)
    • Language English
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    TÃtÃ-Michel Kpomassie was a teenager in Togo when he discovered a book about Greenland—and knew that he must go there. Working his way north over nearly a decade, Kpomassie finally arrived in the country of his dreams. This brilliantly observed and superbly entertaining record of his adventures among the Inuit is a testament both to the wonderful strangeness of the human species and to the surprising sympathies that bind us all.

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    Product details

    • Hardcover 298 pages
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    Former restaurateur Deborah Fabricant takes food to new heights with her stacks of delicious, dramatic edible towers. The over 50 recipes are illustrated with full-color photography and step-by-step photo instructions that make these dishes easy to prepare, yet oh-so-impressive.

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    Product details

    • Paperback 184 pages
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    • Language English
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    Mary Shelley’s groundbreaking classic—begun as a ghost story for friends—is a potent blend of science fiction and horror that has inspired countless movie and other adaptations. Nothing, however, equals the depth and beauty of Shelley’s original, which emains as relevant as ever. In his arrogance, Dr. Victor Frankenstein dreams of discovering the very secret of life…and he succeeds, bringing a new creature into existence. But should man ever play God—and if he does, what does he owe his creation?

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    Product details

    • Series Sterling Unabridged Classics
    • Hardcover 224 pages
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    Product details

    • Series Basic Illustrated Series
    • Paperback 96 pages
    • Publisher Falcon Guides; 1st edition (April 15, 2008)
    • Language English
    • ISBN-10 0762747625
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  • Statistical analysis is coming to hockey in a wave very similar to the one that hit baseball years ago. To prepare the baseball world for the boom in statistics, they needed a guide book that could act as a foundation, and that was Bill James' Baseball Abstract. Hockey, too, needs that guide book a Hockey Abstract that can show how the sport can be viewed through that same type of objective lens that James brought to baseball. At last, it is here. Hockey Abstract is not a textbook, but a guide for how to use analytics to study hockey. Ten questions are answered in a fun and informative way, including who is the best player, goalie or coach, which team will finish first next year, and which was the most lopsided trade in history. Each answer is built on the common foundation of certain key statistics and concepts that are explained in almost as many pages and chapters at the back. Whether you use it as a reference for leading edge research and hard-to-find statistical data, including Vollman's famous Player Usage Charts, or whether you read it for his passionate and engaging story-telling, Hockey Abstract belongs on every serious hockey's fan's bookshelf.
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    Statistical analysis is coming to hockey in a wave very similar to the one that hit baseball years ago. To prepare the baseball world for the boom in statistics, they needed a guide book that could act as a foundation, and that was Bill James' Baseball Abstract. Hockey, too, needs that guide book a Hockey Abstract that can show how the sport can be viewed through that same type of objective lens that James brought to baseball. At last, it is here. Hockey Abstract is not a textbook, but a guide for how to use analytics to study hockey. Ten questions are answered in a fun and informative way, including who is the best player, goalie or coach, which team will finish first next year, and which was the most lopsided trade in history. Each answer is built on the common foundation of certain key statistics and concepts that are explained in almost as many pages and chapters at the back. Whether you use it as a reference for leading edge research and hard-to-find statistical data, including Vollman's famous Player Usage Charts, or whether you read it for his passionate and engaging story-telling, Hockey Abstract belongs on every serious hockey's fan's bookshelf.

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    Product details

    • Paperback 242 pages
    • Publisher CreateSpace Independent Publishing Platform (July 24, 2013)
    • Language English
    • ISBN-10 1490493034
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